MicroRNA199a-Based Post-transcriptional Detargeting of Gene Vectors for Hepatocellular Carcinoma

A gene therapeutic platform needs to be both efficient and safe. The criterion of safety is particularly important for diseases like hepatocellular carcinoma (HCC), which develop in a background of an already compromised liver. Gene vectors can be constructed either by targeting HCC or by detargetin...

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Detalles Bibliográficos
Autores principales: Dhungel, Bijay, Ramlogan-Steel, Charmaine A., Layton, Christopher J., Steel, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148835/
https://www.ncbi.nlm.nih.gov/pubmed/30245470
http://dx.doi.org/10.1016/j.omtn.2018.08.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148835/
https://www.ncbi.nlm.nih.gov/pubmed/30245470
http://dx.doi.org/10.1016/j.omtn.2018.08.016

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