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MicroRNA199a-Based Post-transcriptional Detargeting of Gene Vectors for Hepatocellular Carcinoma
A gene therapeutic platform needs to be both efficient and safe. The criterion of safety is particularly important for diseases like hepatocellular carcinoma (HCC), which develop in a background of an already compromised liver. Gene vectors can be constructed either by targeting HCC or by detargetin...
Autores principales: | Dhungel, Bijay, Ramlogan-Steel, Charmaine A., Layton, Christopher J., Steel, Jason C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148835/ https://www.ncbi.nlm.nih.gov/pubmed/30245470 http://dx.doi.org/10.1016/j.omtn.2018.08.016 |
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