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Production of p-amino-l-phenylalanine (l-PAPA) from glycerol by metabolic grafting of Escherichia coli

BACKGROUND: The non-proteinogenic aromatic amino acid, p-amino-l-phenylalanine (l-PAPA) is a high-value product with a broad field of applications. In nature, l-PAPA occurs as an intermediate of the chloramphenicol biosynthesis pathway in Streptomyces venezuelae. Here we demonstrate that the model o...

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Detalles Bibliográficos
Autores principales: Mohammadi Nargesi, Behrouz, Trachtmann, Natalie, Sprenger, Georg A., Youn, Jung-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148955/
https://www.ncbi.nlm.nih.gov/pubmed/30241531
http://dx.doi.org/10.1186/s12934-018-0996-6