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Role of phosphate limitation and pyruvate decarboxylase in rewiring of the metabolic network for increasing flux towards isoprenoid pathway in a TATA binding protein mutant of Saccharomyces cerevisiae

BACKGROUND: Production of isoprenoids, a large and diverse class of commercially important chemicals, can be achieved through engineering metabolism in microorganisms. Several attempts have been made to reroute metabolic flux towards isoprenoid pathway in yeast. Most approaches have focused on the c...

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Detalles Bibliográficos
Autores principales: Wadhwa, Manisha, Srinivasan, Sumana, Bachhawat, Anand K., Venkatesh, K. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149198/
https://www.ncbi.nlm.nih.gov/pubmed/30241525
http://dx.doi.org/10.1186/s12934-018-1000-1