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Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease Viruses

Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This antiviral potential of innate immunity is mainly attributed to a myriad of IFN-stimulated genes (ISGs). Amongst well-characterized ISGs, we have p...

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Detalles Bibliográficos
Autores principales: Rohaim, Mohammed A., Santhakumar, Diwakar, Naggar, Rania F. El, Iqbal, Munir, Hussein, Hussein A., Munir, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149294/
https://www.ncbi.nlm.nih.gov/pubmed/30271403
http://dx.doi.org/10.3389/fimmu.2018.02025