Synthesis and (In Vitro) Antimycobacterial Activity of Novel N-Arylpiperazines Containing an Ethane-1,2-diyl Connecting Chain

Novel 1-(2-{3-/4-[(alkoxycarbonyl)amino]phenyl}-2-hydroxyethyl)-4-(2-fluorophenyl)-piperazin-1-ium chlorides (alkoxy = methoxy to butoxy; 8a–h) have been designed and synthesized through multistep reactions as a part of on-going research programme focused on finding new antimycobacterials. Lipophili...

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Detalles Bibliográficos
Autores principales: Goněc, Tomáš, Malík, Ivan, Csöllei, Jozef, Jampílek, Josef, Stolaříková, Jiřina, Solovič, Ivan, Mikuš, Peter, Keltošová, Stanislava, Kollár, Peter, O’Mahony, Jim, Coffey, Aidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149664/
https://www.ncbi.nlm.nih.gov/pubmed/29189762
http://dx.doi.org/10.3390/molecules22122100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149664/
https://www.ncbi.nlm.nih.gov/pubmed/29189762
http://dx.doi.org/10.3390/molecules22122100

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