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PTPN2 as a promoter of colon carcinoma via reduction of inflammasome activation

We have recently demonstrated that macrophage-specific loss of Protein tyrosine phosphatase non-receptor type 2 (PTPN2) promotes inflammasome activation, resulting in protection from colorectal cancer. Here we place these findings in context with the role of inflammasomes in colorectal carcinoma, an...

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Detalles Bibliográficos
Autores principales: Spalinger, Marianne R., Scharl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149699/
https://www.ncbi.nlm.nih.gov/pubmed/30250914
http://dx.doi.org/10.1080/23723556.2018.1465013