(−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners

Heat shock proteins (Hsps), amongst them, Hsp70 and Hsp90 families, serve mainly as facilitators of protein folding (molecular chaperones) of the cell. The Hsp70 family of proteins represents one of the most important molecular chaperones in the cell. Plasmodium falciparum, the main agent of malaria...

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Detalles Bibliográficos
Autores principales: Zininga, Tawanda, Ramatsui, Lebogang, Makhado, Pertunia Bveledzani, Makumire, Stanley, Achilinou, Ikechukwu, Hoppe, Heinrich, Dirr, Heini, Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149709/
https://www.ncbi.nlm.nih.gov/pubmed/29206141
http://dx.doi.org/10.3390/molecules22122139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149709/
https://www.ncbi.nlm.nih.gov/pubmed/29206141
http://dx.doi.org/10.3390/molecules22122139

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