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(−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners
Heat shock proteins (Hsps), amongst them, Hsp70 and Hsp90 families, serve mainly as facilitators of protein folding (molecular chaperones) of the cell. The Hsp70 family of proteins represents one of the most important molecular chaperones in the cell. Plasmodium falciparum, the main agent of malaria...
Autores principales: | Zininga, Tawanda, Ramatsui, Lebogang, Makhado, Pertunia Bveledzani, Makumire, Stanley, Achilinou, Ikechukwu, Hoppe, Heinrich, Dirr, Heini, Shonhai, Addmore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149709/ https://www.ncbi.nlm.nih.gov/pubmed/29206141 http://dx.doi.org/10.3390/molecules22122139 |
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