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Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and β-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms

Combining antibiotics with resistance reversing agents is a key strategy to overcome bacterial resistance. Upon screening antimicrobial activities of plants used in traditional medicine, we found that a leaf dichloromethane extract from the shea butter tree (Vitellaria paradoxa) had antimicrobial ac...

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Detalles Bibliográficos
Autores principales: Catteau, Lucy, Reichmann, Nathalie T., Olson, Joshua, Pinho, Mariana G., Nizet, Victor, Van Bambeke, Françoise, Quetin-Leclercq, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149719/
https://www.ncbi.nlm.nih.gov/pubmed/29258194
http://dx.doi.org/10.3390/molecules22122245