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Synthesis of Novel Nitrogen-Containing Heterocycle Bromophenols and Their Interaction with Keap1 Protein by Molecular Docking

We previously reported 5,2’-dibromo-2,4’,5’-trihydroxydiphenylmethanoe (LM49), a bromophenol analogue that shows strong protection from oxidative stress injury owing to its superior anti-inflammatory, antioxidant, and anti-apoptotic properties. A series of novel nitrogen-containing heterocycle bromo...

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Detalles Bibliográficos
Autores principales: Feng, Xiu E., Wang, Qin Jin, Gao, Jie, Ban, Shu Rong, Li, Qing Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149747/
https://www.ncbi.nlm.nih.gov/pubmed/29207575
http://dx.doi.org/10.3390/molecules22122142