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Inhibition by Commercial Aminoglycosides of Human Connexin Hemichannels Expressed in Bacteria

In addition to gap junctional channels that mediate cell-to-cell communication, connexins form hemichannels that are present at the plasma membrane. Since hemichannels are permeable to small hydrophilic compounds, including metabolites and signaling molecules, their abnormal opening can cause or con...

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Detalles Bibliográficos
Autores principales: Fiori, Mariana C., Krishnan, Srinivasan, Kjellgren, Abbey, Cuello, Luis G., Altenberg, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149774/
https://www.ncbi.nlm.nih.gov/pubmed/29186829
http://dx.doi.org/10.3390/molecules22122063