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Inhibition by Commercial Aminoglycosides of Human Connexin Hemichannels Expressed in Bacteria
In addition to gap junctional channels that mediate cell-to-cell communication, connexins form hemichannels that are present at the plasma membrane. Since hemichannels are permeable to small hydrophilic compounds, including metabolites and signaling molecules, their abnormal opening can cause or con...
Autores principales: | Fiori, Mariana C., Krishnan, Srinivasan, Kjellgren, Abbey, Cuello, Luis G., Altenberg, Guillermo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149774/ https://www.ncbi.nlm.nih.gov/pubmed/29186829 http://dx.doi.org/10.3390/molecules22122063 |
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