Cargando…

JAK3 mutations and HOXA9 expression are important cooperating events in T-cell acute lymphoblastic leukemia

Sequencing data from large cohorts of T-cell acute lymphoblastic leukemia patients identified a significant association between the presence of JAK3 mutations and ectopic HOXA9 expression. Mouse models using a constitutive or novel inducible retroviral expression vector to express the JAK3(M511I) mu...

Descripción completa

Detalles Bibliográficos
Autores principales: de Bock, Charles E., Cools, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149783/
https://www.ncbi.nlm.nih.gov/pubmed/30250904
http://dx.doi.org/10.1080/23723556.2018.1458014