A Novel Antibiotic Mechanism of l-Cyclopropylalanine Blocking the Biosynthetic Pathway of Essential Amino Acid l-Leucine

The unusual amino acid l-cyclopropylalanine was isolated from the mushroom Amanita virgineoides after detection in an anti-fungal screening test. l-Cyclopropylalanine was found to exhibit broad-spectrum inhibition against fungi and bacteria. The anti-fungal activity was found to be abolished in the...

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Detalles Bibliográficos
Autores principales: Ma, Bingji, Shen, Jinwen, Yindeeyoungyeon, Wandee, Ruan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149818/
https://www.ncbi.nlm.nih.gov/pubmed/29240717
http://dx.doi.org/10.3390/molecules22122224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149818/
https://www.ncbi.nlm.nih.gov/pubmed/29240717
http://dx.doi.org/10.3390/molecules22122224

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