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Domain IV of Annexin A5 Is Critical for Binding Calcium and Guarantees Its Maximum Binding to the Phosphatidylserine Membrane

Background: Although domain IV of annexin A5 (anxA5) may be less effective in binding phosphatidylserine (PS), the four domains together may guarantee the maximum binding of anxA5 to the PS membrane. Additionally, previous research has shown that annexin mutants lacking one or more domain(s) have di...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Liu, Jing, Cao, Yulu, Hu, Minjin, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149819/
https://www.ncbi.nlm.nih.gov/pubmed/29257055
http://dx.doi.org/10.3390/molecules22122256