A New Series of Pyrrole-Based Chalcones: Synthesis and Evaluation of Antimicrobial Activity, Cytotoxicity, and Genotoxicity

In an effort to develop new potent antimicrobial and anticancer agents, new pyrrole-based chalcones were designed and synthesized via the base-catalyzed Claisen-Schmidt condensation of 2-acetyl-1-methylpyrrole with 5-(aryl)furfural derivatives. The compounds were evaluated for their in vitro antimic...

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Detalles Bibliográficos
Autores principales: Özdemir, Ahmet, Altıntop, Mehlika Dilek, Sever, Belgin, Karaca Gençer, Hülya, Kapkaç, Handan Açelya, Atlı, Özlem, Baysal, Merve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149822/
https://www.ncbi.nlm.nih.gov/pubmed/29189730
http://dx.doi.org/10.3390/molecules22122112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149822/
https://www.ncbi.nlm.nih.gov/pubmed/29189730
http://dx.doi.org/10.3390/molecules22122112

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