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Design and Synthesis of New Benzothiazole Compounds as Selective hMAO-B Inhibitors

In the current work a new class of novel benzothiazole-hydrazone derivatives was designed and synthesized as hMAO-B inhibitors. Structures of the obtained compounds (3a–3j) were characterized by IR, (1)H-NMR, (13)C-NMR, and HRMS spectroscopic methods. The inhibitory activity of compounds (3a–3j) aga...

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Detalles Bibliográficos
Autores principales: Ilgın, Sinem, Osmaniye, Derya, Levent, Serkan, Sağlık, Begüm Nurpelin, Acar Çevik, Ulviye, Çavuşoğlu, Betül Kaya, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149824/
https://www.ncbi.nlm.nih.gov/pubmed/29232838
http://dx.doi.org/10.3390/molecules22122187