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Another one bites the dust; ARTS enables degradation of Bcl-2 by XIAP
ARTS (Sept4_i2) is a pro-apoptotic mitochondrial tumor suppressor protein which binds to and causes degradation of XIAP (X-linked inhibitor of apoptosis). We recently showed that ARTS brings XIAP into close proximity to Bcl-2, creating a complex which enables degradation of both these major anti-apo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149843/ https://www.ncbi.nlm.nih.gov/pubmed/30250908 http://dx.doi.org/10.1080/23723556.2018.1441630 |