One-Pot Lipase-Catalyzed Enantioselective Synthesis of (R)-(−)-N-Benzyl-3-(benzylamino)butanamide: The Effect of Solvent Polarity on Enantioselectivity

The use of the solvent engineering has been applied for controlling the resolution of lipase-catalyzed synthesis of β-aminoacids via Michael addition reactions. The strategy consisted of the thermodynamic control of products at equilibrium using the lipase CalB as a catalyst. The enzymatic chemo- an...

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Detalles Bibliográficos
Autores principales: Ortega-Rojas, Marina A., Rivera-Ramírez, José Domingo, Ávila-Ortiz, C. Gabriela, Juaristi, Eusebio, González-Muñoz, Fernando, Castillo, Edmundo, Escalante, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149857/
https://www.ncbi.nlm.nih.gov/pubmed/29232840
http://dx.doi.org/10.3390/molecules22122189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149857/
https://www.ncbi.nlm.nih.gov/pubmed/29232840
http://dx.doi.org/10.3390/molecules22122189

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