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HIGA: A Running History Information Guided Genetic Algorithm for Protein–Ligand Docking

Protein-ligand docking is an essential part of computer-aided drug design, and it identifies the binding patterns of proteins and ligands by computer simulation. Though Lamarckian genetic algorithm (LGA) has demonstrated excellent performance in terms of protein-ligand docking problems, it can not m...

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Detalles Bibliográficos
Autores principales: Guan, Boxin, Zhang, Changsheng, Zhao, Yuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149887/
https://www.ncbi.nlm.nih.gov/pubmed/29244750
http://dx.doi.org/10.3390/molecules22122233