GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents

A panel of docking scaffolds was developed for the known molecular targets of the anticancer agents, thieno[2,3-b]pyridines, in order to glean insight into their mechanism of action. The reported targets are the copper-trafficking antioxidant 1 protein, tyrosyl DNA phosphodiesterase 1, the colchicin...

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Detalles Bibliográficos
Autores principales: Zafar, Ayesha, Sari, Suat, Leung, Euphemia, Pilkington, Lisa I., van Rensburg, Michelle, Barker, David, Reynisson, Jóhannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149898/
https://www.ncbi.nlm.nih.gov/pubmed/29258235
http://dx.doi.org/10.3390/molecules22122254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149898/
https://www.ncbi.nlm.nih.gov/pubmed/29258235
http://dx.doi.org/10.3390/molecules22122254

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