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Live Fluorescent Staining Platform for Drug-Screening and Mechanism-Analysis in Zebrafish for Bone Mineralization

Currently, drug screening relies on cell-based experiments or on animal models to confirm biological effects. The mammalian system is considered too time-consuming, expensive and complex to perform high-throughput drug screening. There is a gap between in vitro cell-based models and the in vivo mamm...

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Detalles Bibliográficos
Autores principales: Chen, Jung-Ren, Lai, Yu-Heng, Tsai, Jhih-Jie, Hsiao, Chung-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149919/
https://www.ncbi.nlm.nih.gov/pubmed/29186901
http://dx.doi.org/10.3390/molecules22122068