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2-Substituted Aniline as a Simple Scaffold for LuxR-Regulated QS Modulation

The ability of the 2-substituted aniline motif to serve as a scaffold for designing potential LuxR-regulated quorum sensing (QS) modulators has been investigated, using docking experiments and biological evaluation of a series of 15 specially synthesized compounds. Aniline, 2-acetyl-aniline and 2-ni...

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Detalles Bibliográficos
Autores principales: Li, Sizhe, Wawrzyniak, Julien, Queneau, Yves, Soulère, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149922/
https://www.ncbi.nlm.nih.gov/pubmed/29186042
http://dx.doi.org/10.3390/molecules22122090