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Preparation of honokiol nanoparticles by liquid antisolvent precipitation technique, characterization, pharmacokinetics, and evaluation of inhibitory effect on HepG2 cells

BACKGROUND: Honokiol is a bioactive lignanoid and has been utilized in traditional Chinese medicine for a long time. It exhibits several pharmacological properties, such as anticancer effects, anti-inflammatory effects, and antianxiety effects. However, the poor aqueous solubility of honokiol has im...

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Detalles Bibliográficos
Autores principales: Wu, Weiwei, Wang, Li, Wang, Lingling, Zu, Yuangang, Wang, Siying, Liu, Peiyan, Zhao, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149943/
https://www.ncbi.nlm.nih.gov/pubmed/30271141
http://dx.doi.org/10.2147/IJN.S178416