Asparagine, a critical limiting metabolite during glutamine starvation

A challenge of targeting glutamine metabolism in cancer is that tumor cells develop various strategies to adapt to glutamine limitation. We found that asparagine plays a critical role in supporting protein synthesis during glutamine starvation, highlighting a possible approach to optimize the therap...

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Detalles Bibliográficos
Autores principales: Jiang, Jie, Pavlova, Natalya N, Zhang, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Author's Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149945/
https://www.ncbi.nlm.nih.gov/pubmed/30250896
http://dx.doi.org/10.1080/23723556.2018.1441633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149945/
https://www.ncbi.nlm.nih.gov/pubmed/30250896
http://dx.doi.org/10.1080/23723556.2018.1441633

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