From α-Bromomethylbutenolide to Fused Tri(Tetra) Cyclic Dihydrofurandiones through Barbier Reaction–Heck Arylation Sequence

A Barbier reaction–Heck arylation sequence from α-bromomethylbutenolide to fused tri and tetracyclic lactones has been developed. The first step involving a Barbier reaction enabled installing ortho-bromoaromatics in α-ylidene γ-lactones. The latter substrates were subjected to intramolecular Heck r...

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Detalles Bibliográficos
Autores principales: Talbi, Arbia, Gaucher, Anne, Bourdreux, Flavien, Marrot, Jérôme, Efrit, Mohamed L., M’Rabet, Hédi, Prim, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149967/
https://www.ncbi.nlm.nih.gov/pubmed/29292736
http://dx.doi.org/10.3390/molecules22122171