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Vanadium Compounds as PTP Inhibitors

Phosphotyrosine signaling is regulated by the opposing actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). Here we discuss the potential of vanadium derivatives as PTP enzyme inhibitors and metallotherapeutics. We describe how vanadate in the V oxidized state is thou...

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Detalles Bibliográficos
Autores principales: Irving, Elsa, Stoker, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150004/
https://www.ncbi.nlm.nih.gov/pubmed/29257048
http://dx.doi.org/10.3390/molecules22122269