Celastrol enhances Atoh1 expression in inner ear stem cells and promotes their differentiation into functional auditory neuronal-like cells

We aimed to investigate the beneficial effect of Celastrol on inner ear stem cells and potential therapeutic value for hearing loss. The inner ear stem cells were isolated and characterized from utricular sensory epithelium of adult mice. The stemness was evaluated by sphere formation assay. The rel...

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Detalles Bibliográficos
Autores principales: Han, Zhao, Gu, Yu-yan, Cong, Ning, Ma, Rui, Chi, Fang-lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150060/
https://www.ncbi.nlm.nih.gov/pubmed/29902110
http://dx.doi.org/10.1080/15476278.2018.1462433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150060/
https://www.ncbi.nlm.nih.gov/pubmed/29902110
http://dx.doi.org/10.1080/15476278.2018.1462433

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