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Promising molecular mechanisms responsible for gemcitabine resistance in cancer

Gemcitabine is the first-line treatment for pancreatic ductual adenocarcinoma (PDAC) as well as acts against a wide range of other solid tumors. Patients usually have a good initial response to gemcitabine-based chemotherapy but would eventually develop resistance. To improve survival and prognosis...

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Detalles Bibliográficos
Autores principales: Jia, Yanfei, Xie, Jingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150077/
https://www.ncbi.nlm.nih.gov/pubmed/30258872
http://dx.doi.org/10.1016/j.gendis.2015.07.003