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Mitochondria as a therapeutic target in Alzheimer's disease

Alzheimer's disease (AD) remains the most common neurodegenerative disease characterized by β-amyloid protein (Aβ) deposition and memory loss. Studies have shown that mitochondrial dysfunction plays a crucial role in AD, which involves oxidative stress-induced respiratory chain dysfunction, los...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Chen, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150105/
https://www.ncbi.nlm.nih.gov/pubmed/30258891
http://dx.doi.org/10.1016/j.gendis.2016.05.001