Inhibition of bcl-2 and cox-2 Protein Expression after Local Application of a New Carmustine-Loaded Clinoptilolite-Based Delivery System in a Chemically Induced Skin Cancer Model in Mice

Our research has focused on in vitro and in vivo evaluations of a new Carmustine (BCNU)-loaded clinoptilolite-based delivery system. Two clinoptilolite ionic forms—hydrogen form (HCLI) and sodium form (NaCLI)—were prepared, allowing a loading degree of about 5–6 mg BCNU/g of zeolite matrix due to th...

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Detalles Bibliográficos
Autores principales: Ghiciuc, Cristina Mihaela, Strat, Aurel Lulu, Ochiuz, Lacramioara, Lupusoru, Catalina Elena, Ignat, Maria, Vasile, Aurelia, Grigorovici, Alexandru, Stoleriu, Iulian, Solcan, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150160/
https://www.ncbi.nlm.nih.gov/pubmed/29156646
http://dx.doi.org/10.3390/molecules22112014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150160/
https://www.ncbi.nlm.nih.gov/pubmed/29156646
http://dx.doi.org/10.3390/molecules22112014

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