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Practical and Sustainable Synthesis of Optically Pure Levocabastine, a H(1) Receptor Antagonist

A practical and sustainable method for the synthesis of levocabastine hydrochloride (1), a H(1) receptor antagonist for the treatment of allergic conjunctivitis, that can be applied to the industrial production of the compound has been developed. Substantial improvements over the previously reported...

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Detalles Bibliográficos
Autores principales: Kang, Sung Kwon, Nam, Dong Hyuk, Ahn, Jaeseung, Lee, Jaemin, Sim, Jaehoon, Lee, Jeeyeon, Suh, Young-Ger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150193/
https://www.ncbi.nlm.nih.gov/pubmed/29140307
http://dx.doi.org/10.3390/molecules22111971