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Synthesis and Antitumor Activity of Novel Arylpiperazine Derivatives Containing the Saccharin Moiety

Prostate cancer is a major public health problem worldwide. For the development of potential anti-prostate cancer agents, a series of novel arylpiperazine derivatives containing the saccharin moiety based on previous studies was designed, synthesized, and evaluated in prostate (PC-3, LNCaP, and DU14...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Xu, Bing-Bing, Sun, Tao, Zhou, Zhan, Ya, Hui-Yuan, Yuan, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150201/
https://www.ncbi.nlm.nih.gov/pubmed/29109383
http://dx.doi.org/10.3390/molecules22111857