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Transformation of a Thermostable G-Quadruplex Structure into DNA Duplex Driven by Reverse Gyrase

Reverse gyrase is a topoisomerase that can introduce positive supercoils to its substrate DNA. It is demonstrated in our studies that a highly thermal stable G-quadruplex structure in a mini-plasmid DNA was transformed into its duplex conformation after a treatment with reverse gyrase. The structura...

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Detalles Bibliográficos
Autores principales: Li, Dawei, Wang, Qiang, Liu, Yun, Liu, Kun, Zhuge, Qiang, Lv, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150213/
https://www.ncbi.nlm.nih.gov/pubmed/29165328
http://dx.doi.org/10.3390/molecules22112021