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Transformation of a Thermostable G-Quadruplex Structure into DNA Duplex Driven by Reverse Gyrase
Reverse gyrase is a topoisomerase that can introduce positive supercoils to its substrate DNA. It is demonstrated in our studies that a highly thermal stable G-quadruplex structure in a mini-plasmid DNA was transformed into its duplex conformation after a treatment with reverse gyrase. The structura...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150213/ https://www.ncbi.nlm.nih.gov/pubmed/29165328 http://dx.doi.org/10.3390/molecules22112021 |