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Inhibition of Human Kallikrein 5 Protease by Triterpenoids from Natural Sources

Stratum corneum tryptic enzyme kallikrein 5 (KLK5) is a serine protease that is involved in the cell renewal and maintenance of the skin barrier function. The excessive activation of KLK5 causes an exacerbation of dermatoses, such as rosacea and atopic dermatitis. Some triterpenoids are reported to...

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Detalles Bibliográficos
Autores principales: Matsubara, Yosuke, Matsumoto, Takashi, Koseki, Junichi, Kaneko, Atsushi, Aiba, Setsuya, Yamasaki, Kenshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150226/
https://www.ncbi.nlm.nih.gov/pubmed/29077044
http://dx.doi.org/10.3390/molecules22111829