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Simultaneous Determination of Twenty-Five Compounds in Rat Plasma Using Ultra-High Performance Liquid Chromatography-Polarity Switching Tandem Mass Spectrometry and Its Application to a Pharmacokinetic Study

An attempt was made to characterize the pharmacokinetic profiles of Qishen Keli (QSKL) that has been widely proved to be effective in clinical practice. A method using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) for the simultaneous determination...

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Detalles Bibliográficos
Autores principales: Zhang, Na, Li, Yueting, Sun, Jing, Li, Chun, Song, Yuelin, Li, Jun, Tu, Pengfei, Zhao, Yunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150229/
https://www.ncbi.nlm.nih.gov/pubmed/29084165
http://dx.doi.org/10.3390/molecules22111853