Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

A new series of 2-alkyloxy-pyridine-3-carbonitrile-benzofuran hybrids (4a–x) was synthesized. All the new derivatives were examined via the standard technique for their vasodilation activity. Some of the investigated compounds exhibited a remarkable activity, with compounds 4w, 4e, 4r, 4s, 4f and 4g...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalifa, Nagy M., Srour, Aladdin M., Abd El-Karim, Somaia S., Saleh, Dalia O., Al-Omar, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150240/
https://www.ncbi.nlm.nih.gov/pubmed/29072621
http://dx.doi.org/10.3390/molecules22111820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150240/
https://www.ncbi.nlm.nih.gov/pubmed/29072621
http://dx.doi.org/10.3390/molecules22111820

Ejemplares similares