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Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

A new series of 2-alkyloxy-pyridine-3-carbonitrile-benzofuran hybrids (4a–x) was synthesized. All the new derivatives were examined via the standard technique for their vasodilation activity. Some of the investigated compounds exhibited a remarkable activity, with compounds 4w, 4e, 4r, 4s, 4f and 4g...

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Detalles Bibliográficos
Autores principales:	Khalifa, Nagy M., Srour, Aladdin M., Abd El-Karim, Somaia S., Saleh, Dalia O., Al-Omar, Mohamed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150240/ https://www.ncbi.nlm.nih.gov/pubmed/29072621 http://dx.doi.org/10.3390/molecules22111820

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