Design, Synthesis and Preliminary Biological Evaluation of Novel Benzyl Sulfoxide 2-Indolinone Derivatives as Anticancer Agents

In this work, a series of novel benzyl sulfoxide 2-indolinone derivatives was designed and synthesized as potent anticancer agents. Tyrosine kinase inhibitory activity assay indicated that most of the compounds showed significant activity. The in vitro antiproliferative activity of these compounds w...

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Detalles Bibliográficos
Autores principales: Tang, Lin, Peng, Tao, Wang, Gang, Wen, Xiaoxue, Sun, Yunbo, Zhang, Shouguo, Liu, Shuchen, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150246/
https://www.ncbi.nlm.nih.gov/pubmed/29144401
http://dx.doi.org/10.3390/molecules22111979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150246/
https://www.ncbi.nlm.nih.gov/pubmed/29144401
http://dx.doi.org/10.3390/molecules22111979

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