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Design, Synthesis and Preliminary Biological Evaluation of Novel Benzyl Sulfoxide 2-Indolinone Derivatives as Anticancer Agents
In this work, a series of novel benzyl sulfoxide 2-indolinone derivatives was designed and synthesized as potent anticancer agents. Tyrosine kinase inhibitory activity assay indicated that most of the compounds showed significant activity. The in vitro antiproliferative activity of these compounds w...
Autores principales: | Tang, Lin, Peng, Tao, Wang, Gang, Wen, Xiaoxue, Sun, Yunbo, Zhang, Shouguo, Liu, Shuchen, Wang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150246/ https://www.ncbi.nlm.nih.gov/pubmed/29144401 http://dx.doi.org/10.3390/molecules22111979 |
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