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S100A8/A9 promotes parenchymal damage and renal fibrosis in obstructive nephropathy

Despite advances in our understanding of the mechanisms underlying the progression of chronic kidney disease and the development of fibrosis, only limited efficacious therapies exist. The calcium binding protein S100A8/A9 is a damage‐associated molecular pattern which can activate Toll‐like receptor...

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Detalles Bibliográficos
Autores principales: Tammaro, A., Florquin, S., Brok, M., Claessen, N., Butter, L. M., Teske, G. J. D., de Boer, O. J., Vogl, T., Leemans, J. C., Dessing, M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150262/
https://www.ncbi.nlm.nih.gov/pubmed/29746703
http://dx.doi.org/10.1111/cei.13154