Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation

Harmine belongs to a group of β-carboline alkaloids endowed with antitumor properties. Harmine and its derivatives are thought to bind to DNA and interfere with topoisomerase activities. We investigated the base-dependent binding of harmine, and three of its synthetic anticancer-active derivatives t...

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Detalles Bibliográficos
Autores principales: Pagano, Bruno, Caterino, Marco, Filosa, Rosanna, Giancola, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150274/
https://www.ncbi.nlm.nih.gov/pubmed/29077046
http://dx.doi.org/10.3390/molecules22111831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150274/
https://www.ncbi.nlm.nih.gov/pubmed/29077046
http://dx.doi.org/10.3390/molecules22111831

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