Structure-Based Design of Potent and Selective Ligands at the Four Adenosine Receptors

The four receptors that signal for adenosine, A(1), A(2A), A(2B) and A(3) ARs, belong to the superfamily of G protein-coupled receptors (GPCRs). They mediate a number of (patho)physiological functions and have attracted the interest of the biopharmaceutical sector for decades as potential drug targe...

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Detalles Bibliográficos
Autores principales: Jespers, Willem, Oliveira, Ana, Prieto-Díaz, Rubén, Majellaro, María, Åqvist, Johan, Sotelo, Eddy, Gutiérrez-de-Terán, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150288/
https://www.ncbi.nlm.nih.gov/pubmed/29125553
http://dx.doi.org/10.3390/molecules22111945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150288/
https://www.ncbi.nlm.nih.gov/pubmed/29125553
http://dx.doi.org/10.3390/molecules22111945

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