Organocatalytic Access to Enantioenriched Spirooxindole-Based 4-Methyleneazetidines

This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates. The asymmetric induction is secured by an organo...

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Detalles Bibliográficos
Autores principales: Rainoldi, Giulia, Faltracco, Matteo, Spatti, Claudia, Silvani, Alessandra, Lesma, Giordano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150293/
https://www.ncbi.nlm.nih.gov/pubmed/29160827
http://dx.doi.org/10.3390/molecules22112016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150293/
https://www.ncbi.nlm.nih.gov/pubmed/29160827
http://dx.doi.org/10.3390/molecules22112016

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