Cargando…

Organocatalytic Access to Enantioenriched Spirooxindole-Based 4-Methyleneazetidines

This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates. The asymmetric induction is secured by an organo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rainoldi, Giulia, Faltracco, Matteo, Spatti, Claudia, Silvani, Alessandra, Lesma, Giordano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150293/ https://www.ncbi.nlm.nih.gov/pubmed/29160827 http://dx.doi.org/10.3390/molecules22112016

Ejemplares similares

One step access to oxindole-based β-lactams through Ugi four-center three-component reaction
por: Rainoldi, Giulia, et al.
Publicado: (2018)

Solvent-free synthesis of enantioenriched β-silyl nitroalkanes under organocatalytic conditions
por: Dubey, Akhil K, et al.
Publicado: (2021)

New Strategy To Access Enantioenriched Cyclohexadienones: Kinetic Resolution of para-Quinols by Organocatalytic Thiol-Michael Addition Reactions
por: Tang, Ting, et al.
Publicado: (2018)

Prebiotic access to enantioenriched glyceraldehyde mediated by peptides
por: Yu, Jinhan, et al.
Publicado: (2021)

Organocatalytic asymmetric azidation of sulfoxonium ylides: mild synthesis of enantioenriched α-azido ketones bearing a labile tertiary stereocenter
por: Guo, Wengang, et al.
Publicado: (2022)

Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives
por: Lesma, Giordano, et al.
Publicado: (2014)

Copper‐Catalyzed Asymmetric Silylation of Propargyl Dichlorides: Access to Enantioenriched Functionalized Allenylsilanes
por: Liu, Zheng‐Li, et al.
Publicado: (2019)

Stereodivergent Olefination of Enantioenriched Boronic Esters
por: Armstrong, Roly J., et al.
Publicado: (2016)

Accessing Chiral Pyrrolodiketopiperazines under Organocatalytic Conditions
por: Duñabeitia, Eider, et al.
Publicado: (2022)

The diketopiperazine-fused tetrahydro-β-carboline scaffold as a model peptidomimetic with an unusual α-turn secondary structure
por: Airaghi, Francesco, et al.
Publicado: (2013)

Palladium-Catalyzed, Enantioselective Formal Cycloaddition between Benzyltriflamides and Allenes: Straightforward Access to Enantioenriched Isoquinolines
por: Vidal, Xandro, et al.
Publicado: (2019)

Transition metal-catalyzed synthesis of spirooxindoles
por: Saranya, P. V., et al.
Publicado: (2021)

Access to enantioenriched compounds bearing challenging tetrasubstituted stereocenters via kinetic resolution of auxiliary adjacent alcohols
por: Niu, Shengtong, et al.
Publicado: (2021)

Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium
por: Dander, Jacob E., et al.
Publicado: (2019)

Asymmetric Syntheses of Enantioenriched 2,5-Disubstituted Pyrrolidines
por: Lazib, Yanis, et al.
Publicado: (2023)

Organocatalytic atroposelective heterocycloaddition to access axially chiral 2-arylquinolines
por: Yang, Gongming, et al.
Publicado: (2021)

Access to Spirooxindole-Fused Cyclopentanes via a Stereoselective Organocascade Reaction Using Bifunctional Catalysis
por: Vopálenská, Andrea, et al.
Publicado: (2023)

Kinetic Resolution of 2-Aryl-4-methylenepiperidines toward Enantioenriched Functionalizable Piperidine Fragments
por: Choi, Anthony, et al.
Publicado: (2022)

Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis
por: Wagner, Alexander J., et al.
Publicado: (2017)

Radical cascades using enantioenriched 7-azabenzonorbornenes and their applications in synthesis
por: Hodgson, David M, et al.
Publicado: (2008)

Data on for the synthesis of a new enantioenriched bisindolylmethane sulfamate derivatives
por: Kim, Sung-Gon
Publicado: (2019)

Catalytic asymmetric synthesis of enantioenriched α-deuterated pyrrolidine derivatives
por: Chang, Xin, et al.
Publicado: (2022)

Photocatalysis and Kinetic Resolution by Lithiation to Give Enantioenriched 2-Arylpiperazines
por: Das, Anjan, et al.
Publicado: (2023)

Derivatives of Natural Organocatalytic Cofactors and Artificial Organocatalytic Cofactors as Catalysts in Enzymes
por: Lechner, Horst, et al.
Publicado: (2022)

Asymmetric Organocatalytic Homologation: Access to Diverse Chiral Trifluoromethyl Organoboron Species
por: Jayarajan, Ramasamy, et al.
Publicado: (2022)

Construction of Spirooxindole Skeleton Through Intramolecular Dieckmann Cyclization
por: Wu, Ting, et al.
Publicado: (2017)

Spirooxindole: A Versatile Biologically Active Heterocyclic Scaffold
por: Panda, Siva S., et al.
Publicado: (2023)

TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline
por: Sathish, Manda, et al.
Publicado: (2021)

A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A
por: Beck, Jordan C., et al.
Publicado: (2018)

Ring‐to‐Thread Chirality Transfer in [2]Rotaxanes for the Synthesis of Enantioenriched Lactams
por: Lopez‐Leonardo, Carmen, et al.
Publicado: (2022)

Highly enantioselective access to cannabinoid-type tricyles by organocatalytic Diels–Alder reactions
por: Bräse, Stefan, et al.
Publicado: (2012)

Organocatalytic Enantioselective Mannich Reaction: Direct Access to Chiral β-Amino Esters
por: Ravi Kumar, G., et al.
Publicado: (2019)

Expedient Organocatalytic Syntheses of 4-Substituted Pyrazolidines and Isoxazolidines
por: Yousfi, Tarek, et al.
Publicado: (2016)

Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization
por: Dai, Chunhui, et al.
Publicado: (2012)

Titanium(IV)-Catalyzed Stereoselective Synthesis of Spirooxindole-1-pyrrolines
por: Badillo, Joseph J., et al.
Publicado: (2014)

Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins
por: Liu, Zhiwen, et al.
Publicado: (2021)

Straightforward Access to Enantioenriched cis-3-Fluoro-dihydroquinolin-4-ols Derivatives via Ru(II)-Catalyzed-Asymmetric Transfer Hydrogenation/Dynamic Kinetic Resolution
por: Molina Betancourt, Ricardo, et al.
Publicado: (2022)

Organocatalytic Fluorogenic Synthesis of Chromenes
por: Raeisolsadati Oskouei, Mina, et al.
Publicado: (2017)

Catalytic asymmetric radical aminoperfluoroalkylation and aminodifluoromethylation of alkenes to versatile enantioenriched-fluoroalkyl amines
por: Lin, Jin-Shun, et al.
Publicado: (2017)

Intramolecular asymmetric reductive amination: synthesis of enantioenriched dibenz[c,e]azepines
por: Yang, Tao, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_q4pvfhkf6g5qm3qjtrcocen8ep