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Influence of Shenxiong Glucose Injection on the Activities of Six CYP Isozymes and Metabolism of Warfarin in Rats Assessed Using Probe Cocktail and Pharmacokinetic Approaches

Shenxiong glucose injection (SGI), a traditional Chinese medicine (TCM) preparation, has been widely used for the treatment of various cardiovascular and cerebrovascular diseases for many years. We assessed the potential influences of SGI on the activities of six CYP enzymes (CYP1A2, CYP2C11, CYP2C1...

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Detalles Bibliográficos
Autores principales: Sun, Jia, Lu, Yuan, Li, Yueting, Pan, Jie, Liu, Chunhua, Gong, Zipeng, Huang, Jing, Zheng, Jiang, Zheng, Lin, Li, Yongjun, Liu, Ting, Wang, Yonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150296/
https://www.ncbi.nlm.nih.gov/pubmed/29156621
http://dx.doi.org/10.3390/molecules22111994