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Synthesis and Improved Cross-Linking Properties of C5-Modified Furan Bearing PNAs

Over the past decades, peptide nucleic acid/DNA (PNA:DNA) duplex stability has been improved via backbone modification, often achieved via introducing an amino acid side chain at the α- or γ-position in the PNA sequence. It was previously shown that interstrand cross-linking can further enhance the...

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Detalles Bibliográficos
Autores principales: Elskens, Joke, Manicardi, Alex, Costi, Valentina, Madder, Annemieke, Corradini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150320/
https://www.ncbi.nlm.nih.gov/pubmed/29156637
http://dx.doi.org/10.3390/molecules22112010