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Synthesis and Improved Cross-Linking Properties of C5-Modified Furan Bearing PNAs
Over the past decades, peptide nucleic acid/DNA (PNA:DNA) duplex stability has been improved via backbone modification, often achieved via introducing an amino acid side chain at the α- or γ-position in the PNA sequence. It was previously shown that interstrand cross-linking can further enhance the...
Autores principales: | Elskens, Joke, Manicardi, Alex, Costi, Valentina, Madder, Annemieke, Corradini, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150320/ https://www.ncbi.nlm.nih.gov/pubmed/29156637 http://dx.doi.org/10.3390/molecules22112010 |
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